Gene
zbtb18
- ID
- ZDB-GENE-050419-73
- Name
- zinc finger and BTB domain containing 18
- Symbol
- zbtb18 Nomenclature History
- Previous Names
-
- si:ch211-221n23.1
- znf238
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in brain; optic cup; and somite. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 22. Orthologous to human ZBTB18 (zinc finger and BTB domain containing 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 22 | Alliance | Intellectual developmental disorder, autosomal dominant 22 | 612337 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|
|
UniProtKB:Q1L8W0
|
537 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zbtb18-201
(1)
|
Ensembl | 638 nt | ||
| mRNA |
zbtb18-202
(1)
|
Ensembl | 6,971 nt | ||
| mRNA |
zbtb18-203
(1)
|
Ensembl | 2,485 nt |
Interactions and Pathways
No data available
Plasmids