Gene

cngb1a

ID
ZDB-GENE-050419-164
Name
cyclic nucleotide gated channel subunit beta 1a
Symbol
cngb1a Nomenclature History
Previous Names
  • si:ch211-160j6.1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport and visual perception. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 45. Orthologous to human CNGB1 (cyclic nucleotide gated channel subunit beta 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cngb1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 45 Alliance Retinitis pigmentosa 45 613767
Associated With cngb1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
Domain IPR000595 Cyclic nucleotide-binding domain
Family IPR050866 Cyclic nucleotide-gated cation channel
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Homologous_superfamily IPR018490 Cyclic nucleotide-binding domain superfamily
Domain Details Per Protein
Protein Length Cyclic nucleotide-binding, conserved site Cyclic nucleotide-binding domain Cyclic nucleotide-binding domain superfamily Cyclic nucleotide-gated cation channel RmlC-like jelly roll fold
UniProtKB:A0A8M3AV53 1313
UniProtKB:A0A8M3B354 1321
UniProtKB:A0A8N7TBM6 1326
UniProtKB:A0A8M3AJU1 1325
UniProtKB:A0A8M3AJU4 1288
UniProtKB:A0A8M3AS70 1302
UniProtKB:A0A8M3AKM9 1314
UniProtKB:A0A8M2B661 761
UniProtKB:A0A8M9PMQ4 1307
UniProtKB:A0A8M3B358 1034
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cngb1a-201 (1) Ensembl 1,837 nt
mRNA cngb1a-202 (1) Ensembl 2,469 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations