Gene
foxf1
- ID
- ZDB-GENE-050419-153
- Name
- forkhead box F1
- Symbol
- foxf1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in sprouting angiogenesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in persistent fetal circulation syndrome. Is expressed in gut; head; swim bladder; and swim bladder bud. Orthologous to human FOXF1 (forkhead box F1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| persistent fetal circulation syndrome | Alliance | Alveolar capillary dysplasia with misalignment of pulmonary veins | 265380 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018122 | Fork head domain conserved site1 |
| Conserved_site | IPR030456 | Fork head domain conserved site 2 |
| Domain | IPR001766 | Fork head domain |
| Family | IPR051770 | Forkhead box transcription regulator |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Forkhead box transcription regulator | Fork head domain | Fork head domain conserved site1 | Fork head domain conserved site 2 | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A1L1S5
|
380 |
Interactions and Pathways
No data available
Plasmids
No data available