Gene
slc39a8
- ID
- ZDB-GENE-050419-124
- Name
- solute carrier family 39 member 8
- Symbol
- slc39a8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have zinc ion transmembrane transporter activity. Involved in manganese ion transmembrane transport. Predicted to localize to integral component of membrane. Used to study idiopathic scoliosis. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Is expressed in brain; eye; and spinal cord. Orthologous to human SLC39A8 (solute carrier family 39 member 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Haller et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation type IIn | Alliance | Congenital disorder of glycosylation, type IIn | 616721 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| idiopathic scoliosis | slc39a8stl583/stl583 (AB) | standard conditions | Haller et al., 2018 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc/iron permease | Zinc Iron Protein (ZIP) Transporter |
|---|---|---|---|
|
UniProtKB:A0A8M3AYZ5
|
443 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc39a8-201
(1)
|
Ensembl | 1,416 nt | ||
| mRNA |
slc39a8-202
(1)
|
Ensembl | 597 nt |
Interactions and Pathways
No data available
Plasmids
No data available