Gene
pfklb
- ID
- ZDB-GENE-050417-62
- Name
- phosphofructokinase, liver b
- Symbol
- pfklb Nomenclature History
- Previous Names
-
- zgc:110298 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including 6-phosphofructokinase activity; anion binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to act upstream of or within glycolytic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Predicted to be active in membrane. Is expressed in several structures, including liver; male organism; nervous system; somite; and yolk syncytial layer. Orthologous to human PFKL (phosphofructokinase, liver type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110298 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hemolytic anemia due to phosphofructokinase deficiency |
1 - 1 of 1
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR015912 | Phosphofructokinase, conserved site |
| Domain | IPR000023 | Phosphofructokinase domain |
| Family | IPR009161 | ATP-dependent 6-phosphofructokinase, eukaryotic-type |
| Family | IPR022953 | ATP-dependent 6-phosphofructokinase |
| Family | IPR041914 | ATP-dependent 6-phosphofructokinase, vertebrate-type |
1 - 5 of 6 Show all
Domain Details Per Protein
| Protein | Length | ATP-dependent 6-phosphofructokinase | ATP-dependent 6-phosphofructokinase, eukaryotic-type | ATP-dependent 6-phosphofructokinase, vertebrate-type | Phosphofructokinase, conserved site | Phosphofructokinase domain | Phosphofructokinase superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4ID68
|
779 |
1 - 1 of 1
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available