Gene
capn2l
- ID
- ZDB-GENE-050417-341
- Name
- calpain 2, (m/II) large subunit, like
- Symbol
- capn2l Nomenclature History
- Previous Names
-
- wu:fb09d04
- xx:hac23b03
- zgc:112420
- zgc:92480
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis and regulation of cytoskeleton organization. Is expressed in ectoderm; epidermis; lateral line ganglion; pectoral fin; and pharynx. Orthologous to human CAPN2 (calpain 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92480 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR000169 | Cysteine peptidase, cysteine active site |
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR001300 | Peptidase C2, calpain, catalytic domain |
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR022682 | Peptidase C2, calpain, large subunit, domain III |
| Domain | IPR022683 | Peptidase C2, calpain, domain III |
| Domain | IPR033883 | Calpain subdomain III |
| Family | IPR022684 | Peptidase C2, calpain family |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR036213 | Calpain large subunit, domain III superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | Calpain large subunit, domain III superfamily | Calpain subdomain III | Cysteine peptidase, cysteine active site | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Papain-like cysteine peptidase superfamily | Peptidase C2, calpain, catalytic domain | Peptidase C2, calpain, domain III | Peptidase C2, calpain family | Peptidase C2, calpain, large subunit, domain III |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q561U0
|
700 | |||||||||||
|
UniProtKB:A0A0N4SUE6
|
||||||||||||
|
UniProtKB:Q6DFZ8
|
700 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
capn2l-201
(1)
|
Ensembl | 2,597 nt | ||
| mRNA |
capn2l-202
(1)
|
Ensembl | 2,613 nt |
Interactions and Pathways
No data available
Plasmids
No data available