Gene
eed
- ID
- ZDB-GENE-050417-287
- Name
- embryonic ectoderm development
- Symbol
- eed Nomenclature History
- Previous Names
-
- zgc:112509
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to contribute to nucleosome binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization and histone methylation. Predicted to be located in nucleus. Predicted to be part of ESC/E(Z) complex. Is expressed in several structures, including eye; gonad; heart; intestine; and midbrain hindbrain boundary. Orthologous to human EED (embryonic ectoderm development).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112509 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Raby et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cohen-Gibson syndrome | 617561 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR051243 | Polycomb group WD repeat-containing protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Polycomb group WD repeat-containing protein | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1N587
|
441 | |||||
|
UniProtKB:Q566T0
|
443 |
Interactions and Pathways
No data available
Plasmids
No data available