Gene
f3b
- ID
- ZDB-GENE-050417-234
- Name
- coagulation factor IIIb
- Symbol
- f3b Nomenclature History
- Previous Names
-
- TFb (1)
- zgc:112151
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have cytokine receptor activity. Involved in vasculature development. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; disseminated intravascular coagulation; and von Willebrand's disease. Is expressed in hindbrain and otic vesicle. Orthologous to human F3 (coagulation factor III, tissue factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Zhou et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR015373 | Interferon/interleukin receptor domain |
| Family | IPR001187 | Tissue factor |
| Family | IPR050650 | Type II Cytokine and Tissue Factor Receptors |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Interferon/interleukin receptor domain | Tissue factor | Type II Cytokine and Tissue Factor Receptors |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B0UY88
|
288 |
Interactions and Pathways
No data available
Plasmids
No data available