Gene

mfge8a

ID

ZDB-GENE-050327-9

Name

milk fat globule EGF and factor V/VIII domain containing a

Symbol

mfge8a Nomenclature History

Previous Names

mfge8l
im:6895406
zgc:110846

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Human ortholog(s) of this gene implicated in temporal arteritis. Is expressed in central nervous system and ventricular zone. Orthologous to human MFGE8 (milk fat globule EGF and factor V/VIII domain containing).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6895406 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Luo et al., 2023
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mfge8a Human Ortholog

No data available

Associated With mfge8a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000421	Coagulation factor 5/8, C-terminal domain
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Family	IPR050633	Neuropilin/Multicopper Oxidase/Coagulation Factor
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site