Gene
kcnab1a
- ID
- ZDB-GENE-050327-79
- Name
- potassium voltage-gated channel subfamily A regulatory beta subunit 1a
- Symbol
- kcnab1a Nomenclature History
- Previous Names
-
- kcnab1
- zgc:113627 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transport and transmembrane transport. Predicted to localize to cytoplasm and integral component of membrane. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Is expressed in immature eye; myotome; nervous system; pharyngeal arch; and somite. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A member regulatory beta subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7159135 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR023210 | NADP-dependent oxidoreductase domain |
Family | IPR005399 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
Family | IPR005400 | Potassium channel, voltage-dependent, beta subunit, KCNAB1 |
Family | IPR005983 | Potassium channel, voltage-dependent, beta subunit, KCNAB |
Homologous_superfamily | IPR036812 | NADP-dependent oxidoreductase domain superfamily |
Domain Details Per Protein
Protein | Length | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily | Potassium channel, voltage-dependent, beta subunit, KCNAB | Potassium channel, voltage-dependent, beta subunit, KCNAB1 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
---|---|---|---|---|---|---|
UniProtKB:Q58EC4
|
398 | |||||
UniProtKB:A0A8M9PQ73
|
403 | |||||
UniProtKB:A0A8M9PM35
|
423 | |||||
UniProtKB:A0A8M9PFF1
|
406 | |||||
UniProtKB:A0A8M9P126
|
418 | |||||
UniProtKB:A0A8M9PA23
|
411 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
kcnab1a-201
(1)
|
Ensembl | 2273 nt | |
mRNA |
kcnab1a-202
(1)
|
Havana | 2355 nt |
Interactions and Pathways
No data available
Plasmids
No data available