Gene

tufm

ID
ZDB-GENE-050320-73
Name
Tu translation elongation factor, mitochondrial
Symbol
tufm Nomenclature History
Previous Names
  • fi06f04
  • wu:fi06f04
  • zgc:110766
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to act upstream of or within translational elongation. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; pectoral fin bud; and segmental plate. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 4. Orthologous to human TUFM (Tu translation elongation factor, mitochondrial).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tufm Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 4 Alliance Combined oxidative phosphorylation deficiency 4 610678
Associated With tufm Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR031157 Tr-type G domain, conserved site
Domain IPR000795 Translational (tr)-type GTP-binding domain
Domain IPR004160 Translation elongation factor EFTu/EF1A, C-terminal
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Domain IPR033720 Elongation factor Tu, domain 2
Domain IPR041709 Elongation factor Tu (EF-Tu), GTP-binding domain
Family IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle
Family IPR050055 Elongation factor Tu GTPase
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Elongation factor Tu, domain 2 Elongation factor Tu (EF-Tu), GTP-binding domain Elongation factor Tu GTPase P-loop containing nucleoside triphosphate hydrolase Translational (tr)-type GTP-binding domain Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Translation elongation factor EFTu/EF1A, bacterial/organelle Translation elongation factor EFTu/EF1A, C-terminal Translation elongation factor EFTu-like, domain 2 Translation protein, beta-barrel domain superfamily Tr-type G domain, conserved site
UniProtKB:Q5BJ17
InterPro
448
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tufm-201 (1)
Ensembl
Ensembl 1,784 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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