Gene

capn2a

ID

ZDB-GENE-050320-69

Name

calpain 2, (m/II) large subunit a

Symbol

capn2a Nomenclature History

Previous Names

zgc:113590

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytoplasm. Is expressed in brain; embryonic structure; pectoral fin; and retina. Orthologous to human CAPN2 (calpain 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With capn2a Human Ortholog

No data available

Associated With capn2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR000169	Cysteine peptidase, cysteine active site
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR001300	Peptidase C2, calpain, catalytic domain
Domain	IPR002048	EF-hand domain
Domain	IPR022682	Peptidase C2, calpain, large subunit, domain III
Domain	IPR022683	Peptidase C2, calpain, domain III
Domain	IPR033883	Calpain subdomain III
Family	IPR022684	Peptidase C2, calpain family
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR036213	Calpain large subunit, domain III superfamily
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily