Gene
lbx1b
- ID
- ZDB-GENE-050309-27
- Name
- ladybird homeobox 1b
- Symbol
- lbx1b Nomenclature History
- Previous Names
-
- lbx1
- lbx1a (1)
- im:7139117
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in convergent extension and regulation of Wnt signaling pathway. Predicted to localize to nucleus. Is expressed in nervous system; neural plate; neural tube; pectoral fin; and spinal cord neural keel. Orthologous to human LBX1 (ladybird homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139117 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Juárez-Morales et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Central hypoventilation syndrome, congenital, 3 | 619483 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | LBX Family Transcription Factors |
|---|---|---|---|---|---|---|
|
UniProtKB:E7FDX5
|
265 |
Interactions and Pathways
No data available
Plasmids
No data available