Gene
ndufb11
- ID
- ZDB-GENE-050309-25
- Name
- NADH:ubiquinone oxidoreductase subunit B11
- Symbol
- ndufb11 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Involved in heart development and vasculature development. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Is expressed in several structures, including alar plate midbrain region; digestive system; intestinal bulb primordium; optic tectum; and pectoral fin. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6897973 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shehata et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| linear skin defects with multiple congenital anomalies 3 | Alliance | Linear skin defects with multiple congenital anomalies 3 | 300952 |
| nuclear type mitochondrial complex I deficiency 30 | Alliance | ?Mitochondrial complex I deficiency, nuclear type 30 | 301021 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR019329 | NADH:ubiquinone oxidoreductase, ESSS subunit |
Domain Details Per Protein
| Protein | Length | NADH:ubiquinone oxidoreductase, ESSS subunit |
|---|---|---|
|
UniProtKB:Q1LYN0
|
150 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufb11-201
(1)
|
Ensembl | 816 nt |
Interactions and Pathways
No data available
Plasmids
No data available