Gene
gdf9
- ID
- ZDB-GENE-050221-7
- Name
- growth differentiation factor 9
- Symbol
- gdf9 Nomenclature History
- Previous Names
-
- zgc:123030
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity. Acts upstream of or within female sex determination. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in fertilized egg; gonad; and immature gonad. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 14. Orthologous to human GDF9 (growth differentiation factor 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ovarian insufficiency 14 | Alliance | Premature ovarian failure 14 | 618014 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|
|
UniProtKB:Q5MD90
|
418 |
Interactions and Pathways
No data available
Plasmids
No data available