Gene

cilp

ID

ZDB-GENE-050208-76

Name

cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Symbol

cilp Nomenclature History

Previous Names

im:7137994

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in osteoarthritis. Is expressed in myotome; pharyngeal arch 3-7 skeleton; and somite. Orthologous to human CILP (cartilage intermediate layer protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7137994 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cilp Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{Lumbar disc disease, susceptibility to}	603932

Associated With cilp Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR025155	WxxW domain
Family	IPR039675	Cartilage intermediate layer protein 1/2
Homologous_superfamily	IPR008969	Carboxypeptidase-like, regulatory domain superfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat