Gene

onecut3a

ID
ZDB-GENE-050208-744
Name
one cut homeobox 3a
Symbol
onecut3a Nomenclature History
Previous Names
  • onecut3
  • si:ch211-195m2.4
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within liver development. Predicted to be active in nucleus. Is expressed in intestine and liver. Orthologous to human ONECUT3 (one cut homeobox 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Matthews et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Matthews et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa7494Allele with one point mutationUnknownMissenseENU
sa43821Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
1 - 2 of 2
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-onecut3aN/AMatthews et al., 2008
MO2-onecut3aN/AMatthews et al., 2008
1 - 2 of 2
Show
Human Disease
Associated With onecut3a Human Ortholog
No data available
Associated With onecut3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001356 Homeodomain
Domain IPR003350 CUT domain
Family IPR051649 CUT Homeobox Domain-Containing Protein
Homologous_superfamily IPR009057 Homedomain-like superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
1 - 5 of 5
Domain Details Per Protein
Protein Length CUT domain CUT Homeobox Domain-Containing Protein Homedomain-like superfamily Homeodomain Lambda repressor-like, DNA-binding domain superfamily
UniProtKB:A0A8N7T7L6
InterPro
451
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 22
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA onecut3a-201 (1)
Ensembl
Ensembl 1,339 nt
ZFIN BLAST
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-195M2ZFIN Curated Data
1 - 1 of 1
Show
Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_689117 (1)1356 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX088720 (1)190269 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8N7T7L6 (1)451 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanONECUT319
Conserved genome location (synteny) (3)
Amino acid sequence comparison (1)
MouseOnecut310
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
TSV
1 - 3 of 3
Show
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.