Gene

shc2

ID

ZDB-GENE-050208-666

Name

SHC (Src homology 2 domain containing) transforming protein 2

Symbol

shc2 Nomenclature History

Previous Names

si:dkey-94n12.3
zgc:162768

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have receptor tyrosine kinase binding activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to plasma membrane. Orthologous to human SHC2 (SHC adaptor protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Yang et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With shc2 Human Ortholog

No data available

Associated With shc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000980	SH2 domain
Domain	IPR006019	Phosphotyrosine interaction domain, Shc-like
Domain	IPR006020	PTB/PI domain
Domain	IPR035676	SH2 adaptor protein C, SH2 domain
Family	IPR051235	Centrosomal Protein 152/SHC-Transforming Protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR036860	SH2 domain superfamily