Gene

ap3d1

ID

ZDB-GENE-050208-437

Name

adaptor related protein complex 3 subunit delta 1

Symbol

ap3d1 Nomenclature History

Previous Names

si:ch211-129c21.6
wu:fj51g01

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to be involved in several processes, including establishment of protein localization to vacuole; synaptic vesicle membrane organization; and synaptic vesicle transport. Predicted to localize to AP-3 adaptor complex; endosome; and terminal bouton. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome. Orthologous to human AP3D1 (adaptor related protein complex 3 subunit delta 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Neuffer et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ap3d1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Hermansky-Pudlak syndrome 10	617050

Associated With ap3d1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002553	Clathrin/coatomer adaptor, adaptin-like, N-terminal
Domain	IPR010474	AP-3 complex subunit delta domain, metazoa
Family	IPR017105	Adaptor protein complex AP-3, delta subunit
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold

Domain Details Per Protein

Protein	Length	Adaptor protein complex AP-3, delta subunit	AP-3 complex subunit delta domain, metazoa	Armadillo-like helical	Armadillo-type fold	Clathrin/coatomer adaptor, adaptin-like, N-terminal
UniProtKB:A0A8M3AXP5 InterPro	1270
UniProtKB:B7ZUU8 InterPro	1247
UniProtKB:A0A8M3AXQ0 InterPro	1252
UniProtKB:A0A8M3B5I6 InterPro	1262
UniProtKB:A0A8M3AM99 InterPro	1262
UniProtKB:A0A8M3AUQ6 InterPro	1243
UniProtKB:A0A8M3AUQ1 InterPro	1263
UniProtKB:A0A8M3AN10 InterPro	1254

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations