Gene
unc119a2
- ID
- ZDB-GENE-050201-2
- Name
- unc-119 lipid binding chaperone a2
- Symbol
- unc119a2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable lipid binding activity. Acts upstream of or within Kupffer's vesicle development and visual perception. Predicted to be active in intercellular bridge and microtubule cytoskeleton. Is expressed in several structures, including adaxial cell; central nervous system; renal system; solid lens vesicle; and visual system. Human ortholog(s) of this gene implicated in immunodeficiency 13. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wright et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 24 | Alliance | Cone-rod dystrophy 24 | 620342 |
| immunodeficiency 13 | Alliance | ?Immunodeficiency 13 | 615518 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set | PDE6D/unc-119 myristoyl-binding |
|---|---|---|---|---|---|
|
UniProtKB:Q1RM42
|
264 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
unc119b-201
(1)
|
Ensembl | 2,239 nt |
Interactions and Pathways
No data available
Plasmids