Gene
unc119a2
- ID
- ZDB-GENE-050201-2
- Name
- unc-119 lipid binding chaperone a2
- Symbol
- unc119a2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have lipid binding activity. Involved in Kupffer's vesicle development and visual perception. Predicted to localize to intercellular bridge and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in idiopathic CD4-positive T-lymphocytopenia. Is expressed in head and trunk. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wright et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 24 | Alliance | Cone-rod dystrophy 24 | 620342 |
| immunodeficiency 13 | Alliance | ?Immunodeficiency 13 | 615518 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set | PDE6D/unc-119 myristoyl-binding |
|---|---|---|---|---|---|
|
UniProtKB:Q1RM42
|
264 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
unc119b-201
(1)
|
Ensembl | 2,239 nt |
Interactions and Pathways
No data available
Plasmids