Gene

ch25h

ID

ZDB-GENE-041212-81

Name

cholesterol 25-hydroxylase

Symbol

ch25h Nomenclature History

Previous Names

ch25hb (1)
zgc:101688 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have C-4 methylsterol oxidase activity and cholesterol 25-hydroxylase activity. Involved in defense response to virus. Predicted to localize to endoplasmic reticulum membrane. Is expressed in gill; intestine; kidney; liver; and spleen. Orthologous to human CH25H (cholesterol 25-hydroxylase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:101688 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ch25h Human Ortholog

No data available

Associated With ch25h Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006694	Fatty acid hydroxylase
Family	IPR050307	Sterol Desaturase and Related Enzymes

Domain Details Per Protein

Protein	Length	Fatty acid hydroxylase	Sterol Desaturase and Related Enzymes
UniProtKB:Q5PRC0 InterPro	251
UniProtKB:B2GRG2 InterPro	251

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ch25h-201 (1) Ensembl	Ensembl		1,121 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations