Gene
foxj1b
- ID
- ZDB-GENE-041212-76
- Name
- forkhead box J1b
- Symbol
- foxj1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in cilium assembly and embryonic organ morphogenesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Is expressed in several structures, including axis; germ ring; mesoderm; nervous system; and pronephros. Orthologous to human FOXJ1 (forkhead box J1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
primary ciliary dyskinesia 43 | Alliance | Ciliary dyskinesia, primary, 43 | 618699 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018122 | Fork head domain conserved site1 |
Conserved_site | IPR030456 | Fork head domain conserved site 2 |
Domain | IPR001766 | Fork head domain |
Domain | IPR047512 | Forkhead box protein J1, forkhead domain |
Family | IPR047513 | Forkhead box protein J1 |
Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Forkhead box protein J1 | Forkhead box protein J1, forkhead domain | Fork head domain | Fork head domain conserved site1 | Fork head domain conserved site 2 | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:F1R8Z9
|
442 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
foxj1b-201
(1)
|
Ensembl | 2316 nt | |
mRNA |
foxj1b-202
(1)
|
Havana | 828 nt | |
mRNA |
foxj1b-203
(1)
|
Ensembl | 1343 nt |
Interactions and Pathways
No data available
Plasmids
No data available