Gene

foxj1b

ID

ZDB-GENE-041212-76

Name

forkhead box J1b

Symbol

foxj1b Nomenclature History

Previous Names

foxj1.2 (1)
fj67h07
wu:fj67h07 (1)
zgc:101713 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in cilium assembly and embryonic organ morphogenesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Is expressed in several structures, including axis; germ ring; mesoderm; nervous system; and pronephros. Orthologous to human FOXJ1 (forkhead box J1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

20 figures from 17 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With foxj1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
primary ciliary dyskinesia 43	Alliance	Ciliary dyskinesia, primary, 43	618699

Associated With foxj1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018122	Fork head domain conserved site1
Conserved_site	IPR030456	Fork head domain conserved site 2
Domain	IPR001766	Fork head domain
Domain	IPR047512	Forkhead box protein J1, forkhead domain
Family	IPR047513	Forkhead box protein J1
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Forkhead box protein J1	Forkhead box protein J1, forkhead domain	Fork head domain	Fork head domain conserved site1	Fork head domain conserved site 2	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:F1R8Z9 InterPro	442

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	foxj1b-201 (1) Ensembl	Ensembl	2,316 nt	Select Tool ZFIN BLAST
mRNA	foxj1b-202 (1) Ensembl	Ensembl	828 nt	Select Tool
mRNA	foxj1b-203 (1) Ensembl	Ensembl	1,343 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations