Gene
iqcb1
- ID
- ZDB-GENE-041212-47
- Name
- IQ motif containing B1
- Symbol
- iqcb1 Nomenclature History
- Previous Names
-
- nphp5 (1)
- zgc:101792
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have calmodulin binding activity. Involved in opsin transport and pronephros development. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Senior-Loken syndrome; nephronophthisis; and retinitis pigmentosa 3. Orthologous to human IQCB1 (IQ motif containing B1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7146634 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Senior-Loken syndrome | Alliance | Senior-Loken syndrome 5 | 609254 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | IQ calmodulin-binding motif-containing protein 1 | IQ motif, EF-hand binding site | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|
|
UniProtKB:A8KC58
|
295 | |||
|
UniProtKB:Q5PRA5
|
595 | |||
|
UniProtKB:A0A8M9QFC9
|
470 |
Interactions and Pathways
No data available
Plasmids
No data available