Gene

fbxo18

ID

ZDB-GENE-041210-99

Name

F-box DNA helicase 1

Symbol

fbxo18 Nomenclature History

Previous Names

si:dkey-22l11.2

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have 3'-5' DNA helicase activity. Predicted to be involved in double-strand break repair via homologous recombination and replication fork processing. Predicted to localize to nucleus. Orthologous to human FBH1 (F-box DNA helicase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fbxo18 Human Ortholog

No data available

Associated With fbxo18 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001810	F-box domain
Domain	IPR014016	UvrD-like helicase, ATP-binding domain
Domain	IPR014017	UvrD-like DNA helicase, C-terminal
Family	IPR000212	DNA helicase, UvrD/REP type
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036047	F-box-like domain superfamily

Domain Details Per Protein

Protein	Length	DNA helicase, UvrD/REP type	F-box domain	F-box-like domain superfamily	P-loop containing nucleoside triphosphate hydrolase	UvrD-like DNA helicase, C-terminal	UvrD-like helicase, ATP-binding domain
UniProtKB:A0A8M9PHI1 InterPro	1010
UniProtKB:A0A8M6Z5E0 InterPro	1009
UniProtKB:A0A8M3B1M6 InterPro	1011
UniProtKB:E9QBZ9 InterPro	992

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fbxo18-201 (1) Ensembl	Ensembl	3,002 nt	Select Tool ZFIN BLAST
mRNA	fbxo18-202 (1) Ensembl	Ensembl	3,377 nt	Select Tool
mRNA	fbxo18-203 (1) Ensembl	Ensembl	5,834 nt	Select Tool ZFIN BLAST
mRNA	fbxo18-204 (1) Ensembl	Ensembl	5,766 nt	Select Tool ZFIN BLAST
mRNA	fbxo18-205 (1) Ensembl	Ensembl	5,982 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations