Gene
lmod2b
- ID
- ZDB-GENE-041210-356
- Name
- leiomodin 2 (cardiac) b
- Symbol
- lmod2b Nomenclature History
- Previous Names
-
- si:dkey-3n7.4
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable tropomyosin binding activity. Predicted to be involved in muscle contraction and myofibril assembly. Predicted to act upstream of or within pointed-end actin filament capping. Predicted to be active in striated muscle thin filament. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2G. Orthologous to human LMOD2 (leiomodin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 2G | Alliance | Cardiomyopathy, dilated, 2G | 619897 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Leucine-rich repeat domain superfamily | Tropomodulin |
|---|---|---|---|
|
UniProtKB:F1Q5L7
|
596 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lmod2b-201
(1)
|
Ensembl | 1,791 nt | ||
| mRNA |
lmod2b-202
(1)
|
Ensembl | 1,812 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-3N7 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005164493 (1) | |||
| Genomic | GenBank:BX664748 (1) | 206047 nt | ||
| Polypeptide | UniProtKB:F1Q5L7 (1) | 596 aa |
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Ulloa, P.E., Rincón, G., Islas-Trejo, A., Araneda, C., Iturra, P., Neira, R., Medrano, J.F. (2015) RNA Sequencing to Study Gene Expression and SNP Variations Associated with Growth in Zebrafish Fed a Plant Protein-Based Diet. Marine biotechnology (New York, N.Y.). 17(3):353-63
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