Gene
lamb1b
- ID
- ZDB-GENE-041210-197
- Name
- laminin, beta 1b
- Symbol
- lamb1b Nomenclature History
- Previous Names
-
- si:dkey-183c16.5
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have extracellular matrix structural constituent and integrin binding activity. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Predicted to localize to laminin complex. Human ortholog(s) of this gene implicated in autistic disorder and lissencephaly. Is expressed in fin; median fin fold; nervous system; and notochord. Orthologous to human LAMB1 (laminin subunit beta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lissencephaly 5 | Alliance | Lissencephaly 5 | 615191 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EGF-like domain | Laminin IV type B | Laminin/Netrin Extracellular Matrix | Laminin, N-terminal | Laminin-type EGF domain |
|---|---|---|---|---|---|---|
|
UniProtKB:F1REL9
|
1767 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lamb1b-201
(1)
|
Ensembl | 5,573 nt | ||
| mRNA |
lamb1b-202
(1)
|
Ensembl | 5,311 nt |
Interactions and Pathways
No data available
Plasmids
No data available