Gene
socs2
- ID
- ZDB-GENE-041210-171
- Name
- suppressor of cytokine signaling 2
- Symbol
- socs2 Nomenclature History
- Previous Names
-
- si:dkey-202b22.1
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphorylation. Predicted to localize to phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in endometrial cancer and ovarian carcinoma. Orthologous to human SOCS2 (suppressor of cytokine signaling 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001496 | SOCS box domain |
| Domain | IPR028410 | Suppressor of cytokine signalling 2, SOCS box domain |
| Domain | IPR035862 | SOCS2, SH2 domain |
| Homologous_superfamily | IPR036036 | SOCS box-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | SH2 domain | SH2 domain superfamily | SOCS2, SH2 domain | SOCS box domain | SOCS box-like domain superfamily | Suppressor of cytokine signalling 2, SOCS box domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B0EVP5
|
197 | ||||||
|
UniProtKB:A0A8M3ARE8
|
198 |
Interactions and Pathways
No data available
Plasmids
No data available