Gene
ddr2l
- ID
- ZDB-GENE-041210-162
- Name
- discoidin domain receptor family, member 2, like
- Symbol
- ddr2l Nomenclature History
- Previous Names
-
- ddr2
- ddr2b
- ddr2c (1)
- si:ch211-193c2.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable collagen binding activity and protein tyrosine kinase collagen receptor activity. Predicted to be involved in several processes, including positive regulation of kinase activity; positive regulation of neuron projection development; and positive regulation of phosphatidylinositol 3-kinase signaling. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Challa et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008266 | Tyrosine-protein kinase, active site |
| Conserved_site | IPR002011 | Tyrosine-protein kinase, receptor class II, conserved site |
| Domain | IPR000421 | Coagulation factor 5/8, C-terminal domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
| Domain | IPR048525 | Discoidin domain-containing receptor 1/2, DS-like domain |
| Family | IPR050122 | Receptor Tyrosine Kinase |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Coagulation factor 5/8, C-terminal domain | Discoidin domain-containing receptor 1/2, DS-like domain | Galactose-binding-like domain superfamily | Protein kinase domain | Protein kinase-like domain superfamily | Receptor Tyrosine Kinase | Serine-threonine/tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, receptor class II, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8N7T7R5
|
873 | ||||||||||
|
UniProtKB:A0A8M9PQU9
|
873 |
Interactions and Pathways
No data available
Plasmids
No data available