Gene
akr1b1.2
- ID
- ZDB-GENE-041210-132
- Name
- aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2
- Symbol
- akr1b1.2 Nomenclature History
- Previous Names
-
- si:dkey-180p18.9
- zgc:153855
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in arteriosclerosis; cataract; diabetic neuropathy; diabetic retinopathy; and type 2 diabetes mellitus. Orthologous to several human genes including AKR1B1 (aldo-keto reductase family 1 member B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138896 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q1JPZ2
|
316 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
akr1b1 (1 of many)-201
(1)
|
Ensembl | 1,592 nt |
Interactions and Pathways
No data available
Plasmids
No data available