Gene

grip1

ID

ZDB-GENE-041210-125

Name

glutamate receptor interacting protein 1

Symbol

grip1 Nomenclature History

Previous Names

si:dkey-244b23.1
si:dkey-6a5.1

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have glucocorticoid receptor binding activity. Predicted to be involved in neurotransmitter receptor transport, endosome to postsynaptic membrane. Human ortholog(s) of this gene implicated in Fraser syndrome 3. Is expressed in brain; eye; median fin fold; and somite. Orthologous to human GRIP1 (glutamate receptor interacting protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Clark et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With grip1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Fraser syndrome 3	Alliance	Fraser syndrome 3	617667

Associated With grip1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001478	PDZ domain
Domain	IPR041489	PDZ domain 6
Family	IPR043545	Glutamate receptor-interacting protein 1/2
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	Glutamate receptor-interacting protein 1/2	PDZ domain	PDZ domain 6	PDZ superfamily
UniProtKB:A0A8M3ARB1 InterPro	1095
UniProtKB:A0A8M3ARA1 InterPro	1171
UniProtKB:A0A8M3ARI0 InterPro	1191
UniProtKB:Q5TZH0 InterPro	1143
UniProtKB:A0A8M3AYN5 InterPro	1110
UniProtKB:A0A8M3ARI5 InterPro	1165
UniProtKB:A0A8M3B1M2 InterPro	1158
UniProtKB:A0A8M3B8V0 InterPro	1165
UniProtKB:A0A8M3AYN0 InterPro	1162
UniProtKB:A0A8M3B1L8 InterPro	1163
UniProtKB:A0A8M3AYM6 InterPro	1176
UniProtKB:A0A8M3B1L3 InterPro	1178
UniProtKB:A0A8M3B8V4 InterPro	1138
UniProtKB:A0A8M3ARJ0 InterPro	1123
UniProtKB:A0A8M3ARA6 InterPro	1143

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	grip1-201 (1) Ensembl	Ensembl	3,610 nt	Select Tool
mRNA	grip1-204 (1) Ensembl	Ensembl	3,471 nt	Select Tool ZFIN BLAST
mRNA	grip1-205 (1) Ensembl	Ensembl	3,792 nt	Select Tool ZFIN BLAST
ncRNA	grip1-002 (1) Ensembl	Ensembl	830 nt	Select Tool
ncRNA	grip1-003 (1) Ensembl	Ensembl	586 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations