Gene
tmem63a
- ID
- ZDB-GENE-041210-107
- Name
- transmembrane protein 63A
- Symbol
- tmem63a Nomenclature History
- Previous Names
-
- si:ch211-117l16.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable calcium activated cation channel activity. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human TMEM63A (transmembrane protein 63A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypomyelinating leukodystrophy 19 | Alliance | Leukodystrophy, hypomyelinating, 19, transient infantile | 618688 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calcium permeable stress-gated cation channel 1-like | CSC1/OSCA1-like, 7TM region | CSC1/OSCA1-like, cytosolic domain | CSC1/OSCA1-like, N-terminal transmembrane domain |
|---|---|---|---|---|---|
|
UniProtKB:A4QP59
|
802 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem63a-201
(1)
|
Ensembl | 2,958 nt |
Interactions and Pathways
No data available
Plasmids
No data available