Gene

nansb

ID
ZDB-GENE-041114-125
Name
N-acetylneuraminic acid synthase b
Symbol
nansb Nomenclature History
Previous Names
  • zgc:101549 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have catalytic activity. Predicted to be involved in carbohydrate biosynthetic process. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Genevieve-type. Orthologous to human NANS (N-acetylneuraminate synthase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhang et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nansb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spondyloepimetaphyseal dysplasia, Genevieve-type Alliance Spondyloepimetaphyseal dysplasia, Genevieve type 610442
Associated With nansb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal
Domain IPR013132 N-acetylneuraminic acid synthase, N-terminal
Domain IPR013974 SAF domain
Family IPR051690 Nonulosonic Acid Synthase
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Homologous_superfamily IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily N-acetylneuraminic acid synthase, N-terminal Nonulosonic Acid Synthase SAF domain
UniProtKB:Q5U3W7 352
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations