Gene

cfhl2

ID

ZDB-GENE-041114-123

Name

complement factor H like 2

Symbol

cfhl2 Nomenclature History

Previous Names

zgc:101554

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in acute myeloid leukemia; age related macular degeneration 1; atypical hemolytic-uremic syndrome; and multiple myeloma. Is expressed in several structures, including digestive system; eye; gill; heart; and yolk syncytial layer. Orthologous to several human genes including F13B (coagulation factor XIII B chain); CFHR1 (complement factor H related 1); and CFHR2 (complement factor H related 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101554 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cfhl2 Human Ortholog

No data available

Associated With cfhl2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000436	Sushi/SCR/CCP domain
Family	IPR051503	Complement System Regulators and Virion Entry Mediators
Homologous_superfamily	IPR035976	Sushi/SCR/CCP superfamily