Gene

colec11

ID

ZDB-GENE-041114-11

Name

collectin sub-family member 11

Symbol

colec11 Nomenclature History

Previous Names

wu:fb82e09
zgc:103572

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have several functions, including calcium ion binding activity; calcium-dependent carbohydrate binding activity; and monosaccharide binding activity. Involved in neural crest cell migration. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in 3MC syndrome 2. Is expressed in head; hindbrain; liver; pronephric duct; and pronephric glomerulus. Orthologous to human COLEC11 (collectin subfamily member 11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Rooryck et al., 2011

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Rooryck et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With colec11 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
3MC syndrome 2	Alliance	3MC syndrome 2	265050

Associated With colec11 Via Experimental Models

Human Disease	Fish	Conditions	Citations
cleft palate	WT + MO1-colec11 + MO2-colec11	standard conditions	Rooryck et al., 2011

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018378	C-type lectin, conserved site
Domain	IPR001304	C-type lectin-like
Domain	IPR033990	Collectin, C-type lectin-like domain
Family	IPR050801	Calcium-Dependent Lectins in Immunity and Development
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Repeat	IPR008160	Collagen triple helix repeat