Gene
cyp3c3
- ID
- ZDB-GENE-041114-102
- Name
- cytochrome P450, family 3, subfamily c, polypeptide 3
- Symbol
- cyp3c3 Nomenclature History
- Previous Names
-
- cyp3c1l2 (1)
- zgc:101781
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have steroid hydroxylase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Is expressed in several structures, including adaxial cell; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101781 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:E9QEE5
|
503 | |||||
|
UniProtKB:A0A8M6Z4Z2
|
503 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp3c3-201
(1)
|
Ensembl | 2,225 nt |
Interactions and Pathways
No data available
Plasmids
No data available