Gene
ino80
- ID
- ZDB-GENE-041014-72
- Name
- INO80 complex ATPase subunit
- Symbol
- ino80 Nomenclature History
- Previous Names
-
- si:ch211-244p18.3
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable ATP hydrolysis activity and histone binding activity. Predicted to be involved in DNA repair and regulation of transcription from RNA polymerase II promoter in response to stress. Predicted to act upstream of or within DNA-templated transcription; cellular response to DNA damage stimulus; and chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of Ino80 complex. Orthologous to human INO80 (INO80 complex ATPase subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ding et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shin et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000330 | SNF2, N-terminal |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR020838 | DBINO domain |
| Domain | IPR031047 | DNA helicase INO80, DEAQ-box helicase domain |
| Domain | IPR049730 | SNF2/RAD5-like, C-terminal helicase domain |
| Family | IPR050520 | INO80/SWR1 chromatin remodeling helicase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | DBINO domain | DNA helicase INO80, DEAQ-box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | INO80/SWR1 chromatin remodeling helicase | P-loop containing nucleoside triphosphate hydrolase | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | SNF2/RAD5-like, C-terminal helicase domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3ARX1
|
1558 | |||||||||
|
UniProtKB:Q5SPB7
|
1552 | |||||||||
|
UniProtKB:A0A8M3B1Z5
|
1557 | |||||||||
|
UniProtKB:A0A8M3AZ14
|
1556 |
Interactions and Pathways
No data available
Plasmids
No data available