Gene

mysm1

ID

ZDB-GENE-041014-28

Name

Myb-like, SWIRM and MPN domains 1

Symbol

mysm1 Nomenclature History

Previous Names

im:7153144
si:ch211-59d15.8

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have histone binding activity; peptidase activity, acting on L-amino acid peptides; and transcription coactivator activity. Involved in cranial skeletal system development. Predicted to localize to SWI/SNF complex. Human ortholog(s) of this gene implicated in diabetic retinopathy. Orthologous to human MYSM1 (Myb like, SWIRM and MPN domains 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7153144 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mysm1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Bone marrow failure syndrome 4	618116

Associated With mysm1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000555	JAB1/MPN/MOV34 metalloenzyme domain
Domain	IPR001005	SANT/Myb domain
Domain	IPR007526	SWIRM domain
Domain	IPR017884	SANT domain
Domain	IPR017930	Myb domain
Domain	IPR037518	MPN domain
Family	IPR050242	JAMM/MPN+ metalloenzymes, peptidase M67A
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily