Gene
stmn2a
- ID
- ZDB-GENE-041010-85
- Name
- stathmin 2a
- Symbol
- stmn2a Nomenclature History
- Previous Names
-
- SCG10b (1)
- zgc:92905
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable tubulin binding activity. Acts upstream of or within nervous system development. Predicted to be active in cytoplasm and growth cone. Is expressed in gut; head; nervous system; spinal cord neural tube; and trigeminal placode. Orthologous to human STMN2 (stathmin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92905 (26 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Stathmin family | Stathmin superfamily |
|---|---|---|---|
|
UniProtKB:E7FE68
|
180 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stmn2a-201
(1)
|
Ensembl | 2,102 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-237B12 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-43F15 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192043 | ZFIN Curated Data | |
| Has Artifact | cDNA | MGC:92905 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001005923 (1) | 2138 nt | ||
| Genomic | GenBank:BX248082 (1) | 152455 nt | ||
| Polypeptide | UniProtKB:E7FE68 (1) | 180 aa |
- Jing, Y., Luo, Y., Li, L., Liu, M., Liu, J.X. (2024) Deficiency of copper responsive gene stmn4 induces retinal developmental defects. Cell biology and toxicology. 40:22
- Shen, W.Y., Fu, X.H., Cai, J., Li, W.C., Fan, B.Y., Pang, Y.L., Zhao, C.X., Abula, M., Kong, X.H., Yao, X., Feng, S.Q. (2022) Identification of key genes involved in recovery from spinal cord injury in adult zebrafish. Neural regeneration research. 17:1334-1342
- Carretero-Rodriguez, L., Guðjónsdóttir, R., Poparic, I., Reilly, M.L., Chol, M., Bianco, I.H., Chiapello, M., Feret, R., Deery, M.J., Guthrie, S. (2021) The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system. The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(31):6652-6672
- Metikala, S., Casie Chetty, S., Sumanas, S. (2021) Single-cell transcriptome analysis of the zebrafish embryonic trunk. PLoS One. 16:e0254024
- Zuccarini, G., D'Atri, I., Cottone, E., Mackie, K., Shainer, I., Gothilf, Y., Provero, P., Bovolin, P., Merlo, G.R. (2019) Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos. International Journal of Molecular Sciences. 21(1):
- Zimmerman, M.W., Liu, Y., He, S., Durbin, A.D., Abraham, B.J., Easton, J., Shao, Y., Xu, B., Zhu, S., Zhang, X., Li, Z., Weichert-Leahey, N., Young, R.A., Zhang, J., Look, A.T. (2018) MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer discovery. 8:320-335
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Lin, M.J., Lee, S.J. (2016) Stathmin-like 4 is critical for the maintenance of neural progenitor cells in dorsal midbrain of zebrafish larvae. Scientific Reports. 6:36188
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Alves, M.M., Burzynski, G., Delalande, J.M., Osinga, J., van der Goot, A., Dolga, A.M., de Graaff, E., Brooks, A.S., Metzger, M., Eisel, U.L., Shepherd, I., Eggen, B.J., and Hofstra, R.M. (2010) KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation. Human molecular genetics. 19(18):3642-3651
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