Gene
serpina7
- ID
- ZDB-GENE-041010-47
- Name
- serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
- Symbol
- serpina7 Nomenclature History
- Previous Names
-
- wu:fb66f08
- wu:fb68e04
- zgc:103617
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Is expressed in blood and liver. Orthologous to several human genes including SERPINA1 (serpin family A member 1); SERPINA12 (serpin family A member 12); and SERPINA7 (serpin family A member 7).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103617 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
[Thyroxine-binding globulin QTL] | 300932 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR023795 | Serpin, conserved site |
Domain | IPR023796 | Serpin domain |
Family | IPR000215 | Serpin family |
Homologous_superfamily | IPR036186 | Serpin superfamily |
Homologous_superfamily | IPR042178 | Serpin superfamily, domain 1 |
Homologous_superfamily | IPR042185 | Serpin superfamily, domain 2 |
Domain Details Per Protein
Protein | Length | Serpin, conserved site | Serpin domain | Serpin family | Serpin superfamily | Serpin superfamily, domain 1 | Serpin superfamily, domain 2 |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QE74
|
425 | ||||||
UniProtKB:F8W5C3
|
410 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
serpina7-201
(1)
|
Ensembl | 1,441 nt | ||
mRNA |
serpina7-202
(1)
|
Ensembl | 1,499 nt |
Interactions and Pathways
No data available
Plasmids
No data available