Gene

nln

ID
ZDB-GENE-041010-216
Name
neurolysin (metallopeptidase M3 family)
Symbol
nln Nomenclature History
Previous Names
  • thop1
  • zgc:92589
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and proteolysis. Predicted to localize to mitochondrial intermembrane space. Is expressed in hypaxial myotome region; musculature system; myotome; and pectoral fin musculature. Orthologous to human NLN (neurolysin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nln Human Ortholog
No data available
Associated With nln Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001567 Peptidase M3A/M3B catalytic domain
Family IPR045090 Peptidase M3A/M3B
Homologous_superfamily IPR024077 Neurolysin/Thimet oligopeptidase, domain 2
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal
Domain Details Per Protein
Protein Length Metallopeptidase, catalytic domain superfamily Neurolysin/Thimet oligopeptidase, domain 2 Neurolysin/Thimet oligopeptidase, N-terminal Peptidase M3A/M3B Peptidase M3A/M3B catalytic domain
UniProtKB:Q5XIZ1 660
UniProtKB:A0A8M6Z2X4 589
UniProtKB:A0A2R8RVE2 710
UniProtKB:A0A8M2B1N0 687
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nln-201 (1) Ensembl 2,094 nt
mRNA nln-202 (1) Ensembl 6,000 nt
mRNA nln-203 (1) Ensembl 6,060 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations