Gene

exosc9

ID

ZDB-GENE-041010-180

Name

exosome component 9

Symbol

exosc9 Nomenclature History

Previous Names

im:6909054
zgc:101680 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have AU-rich element binding activity. Predicted to be involved in RNA metabolic process. Predicted to localize to cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human EXOSC9 (exosome component 9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6909054 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With exosc9 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
pontocerebellar hypoplasia type 1D	Alliance	Pontocerebellar hypoplasia, type 1D	618065

Associated With exosc9 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001247	Exoribonuclease, phosphorolytic domain 1
Domain	IPR015847	Exoribonuclease, phosphorolytic domain 2
Family	IPR033100	Exosome complex component RRP45
Family	IPR050590	Exosome complex component Rrp42 subfamily
Homologous_superfamily	IPR020568	Ribosomal protein uS5 domain 2-type superfamily
Homologous_superfamily	IPR027408	PNPase/RNase PH domain superfamily
Homologous_superfamily	IPR036345	Exoribonuclease, PH domain 2 superfamily