Gene

ppl

ID
ZDB-GENE-041008-196
Name
periplakin
Symbol
ppl Nomenclature History
Previous Names
  • cb180 (1)
  • im:7140067
  • im:7149519
  • sb:cb180
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Predicted to be involved in intermediate filament cytoskeleton organization and wound healing. Predicted to colocalize with intermediate filament. Is expressed in several structures, including EVL; digestive system; fin; periderm; and sensory system. Orthologous to human PPL (periplakin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Inaba et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppl Human Ortholog
No data available
Associated With ppl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR041615 Desmoplakin, SH3 domain
Family IPR043197 Plakin
Homologous_superfamily IPR035915 Plakin repeat superfamily
Repeat IPR001101 Plectin repeat
Repeat IPR018159 Spectrin/alpha-actinin
Domain Details Per Protein
Protein Length Desmoplakin, SH3 domain Plakin Plakin repeat superfamily Plectin repeat SH3 domain Spectrin/alpha-actinin
UniProtKB:A0A0R4IAS2 1754
UniProtKB:A0A286YAI4 1752
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ppl-201 (1) Ensembl 5,905 nt
mRNA ppl-202 (1) Ensembl 5,899 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations