Gene

hook1

ID

ZDB-GENE-041001-159

Name

hook microtubule-tethering protein 1

Symbol

hook1 Nomenclature History

Previous Names

si:dkey-183n20.14

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable dynein light intermediate chain binding activity and microtubule binding activity. Predicted to be involved in several processes, including cytoplasmic microtubule organization; early endosome to late endosome transport; and endosome to lysosome transport. Predicted to act upstream of or within protein transport. Predicted to be located in microtubule. Predicted to be part of FHF complex. Predicted to be active in centrosome and cytoplasm. Orthologous to human HOOK1 (hook microtubule tethering protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hook1 Human Ortholog

No data available

Associated With hook1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR008636	Hook, C-terminal
Domain	IPR043936	HOOK, N-terminal
Homologous_superfamily	IPR036872	CH domain superfamily