Gene
sel1l
- ID
- ZDB-GENE-041001-122
- Name
- SEL1L adaptor subunit of SYVN1 ubiquitin ligase
- Symbol
- sel1l Nomenclature History
- Previous Names
-
- fj60e07
- si:dkey-177p2.3 (1)
- wu:fj60e07
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to localize to Hrd1p ubiquitin ligase ERAD-L complex. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in several structures, including digestive system; eye; hatching gland; pleuroperitoneal region; and polster. Orthologous to several human genes including SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1578 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Barbieri et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000562 | Fibronectin type II domain |
| Family | IPR050767 | Sel1/AlgK |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR013806 | Kringle-like fold |
| Homologous_superfamily | IPR036943 | Fibronectin type II domain superfamily |
| Repeat | IPR006597 | Sel1-like repeat |
Domain Details Per Protein
| Protein | Length | Fibronectin type II domain | Fibronectin type II domain superfamily | Kringle-like fold | Sel1/AlgK | Sel1-like repeat | Tetratricopeptide-like helical domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5RIK6
|
776 |
Interactions and Pathways
No data available
Plasmids
No data available