Gene
cnot3a
- ID
- ZDB-GENE-040927-6
- Name
- CCR4-NOT transcription complex, subunit 3a
- Symbol
- cnot3a Nomenclature History
- Previous Names
-
- fb73b06
- fc17h07
- wu:fb73b06
- wu:fc17h07
- zgc:92813
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to be involved in negative regulation of translation and nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Predicted to localize to CCR4-NOT core complex and P-body. Is expressed in several structures, including gut; head; heart; integument; and testis. Orthologous to human CNOT3 (CCR4-NOT transcription complex subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Delacruz et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Delacruz et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with speech delay, autism, and dysmorphic facies | 618672 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR007207 | CCR4-Not complex component, Not N-terminal domain |
| Domain | IPR007282 | NOT2/NOT3/NOT5, C-terminal |
| Family | IPR012270 | CCR4-NOT complex, subunit 3/ 5 |
| Family | IPR040168 | Not2/Not3/Not5 |
| Homologous_superfamily | IPR038635 | CCR4-NOT complex subunit 2/3/5, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CCR4-Not complex component, Not N-terminal domain | CCR4-NOT complex subunit 2/3/5, C-terminal domain superfamily | CCR4-NOT complex, subunit 3/ 5 | Not2/Not3/Not5 | NOT2/NOT3/NOT5, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:E9QGK5
|
901 | |||||
|
UniProtKB:F1Q4L8
|
908 | |||||
|
UniProtKB:A0A8M9P7W2
|
906 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cnot3a-201
(1)
|
Ensembl | 4,220 nt | ||
| mRNA |
cnot3a-203
(1)
|
Ensembl | 4,198 nt | ||
| ncRNA |
cnot3a-003
(1)
|
Ensembl | 634 nt |
Interactions and Pathways
No data available
Plasmids
No data available