Gene
tspan7
- ID
- ZDB-GENE-040927-5
- Name
- tetraspanin 7
- Symbol
- tspan7 Nomenclature History
- Previous Names
-
- tspan7b
- tm4sf2b (1)
- wu:fb53h11
- zgc:92829
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Is expressed in basal plate midbrain region; nervous system; notochord; and pancreatic bud. Orthologous to human TSPAN7 (tetraspanin 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92829 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 58 | Alliance | Intellectual developmental disorder, X-linked 58 | 300210 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tetraspanin-6/7, EC2 domain | Tetraspanin, animals | Tetraspanin, conserved site | Tetraspanin, EC2 domain superfamily | Tetraspanin/Peripherin |
|---|---|---|---|---|---|---|
|
UniProtKB:B0VEQ2
|
249 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tspan7b-201
(1)
|
Ensembl | 2,891 nt |
Interactions and Pathways
No data available
Plasmids
No data available