Gene

rbfox1

ID

ZDB-GENE-040927-11

Name

RNA binding fox-1 homolog 1

Symbol

rbfox1 Nomenclature History

Previous Names

a2bp1
zgc:103635 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have mRNA binding activity. Involved in heart contraction; hypothalamus development; and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to cytoplasm and nucleus. Is expressed in digestive system; heart; nervous system; neural keel; and skeletal muscle. Orthologous to human RBFOX1 (RNA binding fox-1 homolog 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:103635 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rbfox1 Human Ortholog

No data available

Associated With rbfox1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR025670	Fox-1 C-terminal domain
Domain	IPR034237	FOX1, RNA recognition motif
Family	IPR017325	RNA binding protein fox-1 homolog 1-3
Family	IPR047131	RNA binding protein fox-1 homolog 1-like
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Fox-1 C-terminal domain	FOX1, RNA recognition motif	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA binding protein fox-1 homolog 1-3	RNA binding protein fox-1 homolog 1-like	RNA recognition motif domain
UniProtKB:A0A8M6YYC7 InterPro	377
UniProtKB:A0A8M9PY79 InterPro	368
UniProtKB:A0A8M9PMK8 InterPro	362
UniProtKB:A0A8M9PY74 InterPro	391
UniProtKB:A0A8M6YWH6 InterPro	355
UniProtKB:A0A8M9P6C2 InterPro	364
UniProtKB:A0A8M6YWH2 InterPro	395
UniProtKB:A0A8M9PUS3 InterPro	388
UniProtKB:A0A8M9PY70 InterPro	394
UniProtKB:A0A8M9P6B9 InterPro	377
UniProtKB:A0A8M9PUS8 InterPro	364
UniProtKB:Q642J5 InterPro	373
UniProtKB:A0A8M6YVW0 InterPro	372
UniProtKB:A0A8M6Z4X9 InterPro	375
UniProtKB:A0A8M9PY89 InterPro	337

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rbfox1-202 (1) Ensembl	Ensembl	3,190 nt	Select Tool
mRNA	rbfox1-203 (1) Ensembl	Ensembl	944 nt	Select Tool
mRNA	rbfox1-204 (1) Ensembl	Ensembl	759 nt	Select Tool
mRNA	rbfox1-205 (1) Ensembl	Ensembl	774 nt	Select Tool
mRNA	rbfox1-206 (1) Ensembl	Ensembl	865 nt	Select Tool
mRNA	rbfox1-207 (1) Ensembl	Ensembl	4,963 nt	Select Tool ZFIN BLAST
mRNA	rbfox1-208 (1) Ensembl	Ensembl	4,987 nt	Select Tool ZFIN BLAST
ncRNA	rbfox1-002 (1) Ensembl	Ensembl	662 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations