Gene

vps33a

ID

ZDB-GENE-040914-82

Name

VPS33A core subunit of CORVET and HOPS complexes

Symbol

vps33a Nomenclature History

Previous Names

im:7136893
wu:fc08g01
wu:fc26c10

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to act upstream of or within protein transport and vesicle docking involved in exocytosis. Predicted to be located in late endosome membrane and lysosomal membrane. Predicted to be part of CORVET complex. Predicted to be active in lysosome. Orthologous to human VPS33A (VPS33A core subunit of CORVET and HOPS complexes).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7136893 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vps33a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Mucopolysaccharidosis-plus syndrome	617303

Associated With vps33a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR001619	Sec1-like protein
Homologous_superfamily	IPR027482	Sec1-like, domain 2
Homologous_superfamily	IPR036045	Sec1-like superfamily
Homologous_superfamily	IPR043127	Sec1-like, domain 3a
Homologous_superfamily	IPR043154	Sec1-like, domain 1
Homologous_superfamily	IPR043155	Vacuolar protein sorting-associated protein 33, domain 3b