Gene

tgm2a

ID

ZDB-GENE-040912-78

Name

transglutaminase 2, C polypeptide A

Symbol

tgm2a Nomenclature History

Previous Names

TG2c (1)
tgm2
zgc:101081

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking. Predicted to localize to mitochondrion. Is expressed in muscle; myotome; skeletal muscle; and somite. Orthologous to human TGM2 (transglutaminase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7137767 (2 images)
IMAGE:7146244 (3 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tgm2a Human Ortholog

No data available

Associated With tgm2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR013808	Transglutaminase, active site
Domain	IPR001102	Transglutaminase, N-terminal
Domain	IPR002931	Transglutaminase-like
Domain	IPR008958	Transglutaminase, C-terminal
Family	IPR023608	Protein-glutamine gamma-glutamyltransferase, animal
Family	IPR050779	Protein-glutamine gamma-glutamyltransferases
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Homologous_superfamily	IPR036238	Transglutaminase, C-terminal domain superfamily
Homologous_superfamily	IPR036985	Transglutaminase-like superfamily
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily

Domain Details Per Protein

Protein	Length	Immunoglobulin E-set	Immunoglobulin-like fold	Papain-like cysteine peptidase superfamily	Protein-glutamine gamma-glutamyltransferase, animal	Protein-glutamine gamma-glutamyltransferases	Transglutaminase, active site	Transglutaminase, C-terminal	Transglutaminase, C-terminal domain superfamily	Transglutaminase-like	Transglutaminase-like superfamily	Transglutaminase, N-terminal
UniProtKB:Q66L63 InterPro	679

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tgm2a-201 (1) Ensembl	Ensembl	2,120 nt	Select Tool ZFIN BLAST
ncRNA	ottdart00000062056 (1) Ensembl	Ensembl	976 nt	Select Tool ZFIN BLAST
ncRNA	ottdart00000062057 (1) Ensembl	Ensembl	788 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations