Gene
pnp5b
- ID
- ZDB-GENE-040912-54
- Name
- purine nucleoside phosphorylase 5b
- Symbol
- pnp5b Nomenclature History
- Previous Names
-
- zgc:101740 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable purine-nucleoside phosphorylase activity. Predicted to act upstream of or within nucleoside metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human PNP (purine nucleoside phosphorylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101740 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018099 | Purine phosphorylase, family 2, conserved site |
| Domain | IPR000845 | Nucleoside phosphorylase domain |
| Family | IPR011268 | Purine nucleoside phosphorylase |
| Family | IPR011270 | Purine nucleoside phosphorylase I, inosine/guanosine-specific |
| Homologous_superfamily | IPR035994 | Nucleoside phosphorylase superfamily |
Domain Details Per Protein
| Protein | Length | Nucleoside phosphorylase domain | Nucleoside phosphorylase superfamily | Purine nucleoside phosphorylase | Purine nucleoside phosphorylase I, inosine/guanosine-specific | Purine phosphorylase, family 2, conserved site |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z934
|
193 | |||||
|
UniProtKB:Q66ID4
|
294 | |||||
|
UniProtKB:A0A8M9PW07
|
210 |
Interactions and Pathways
No data available
Plasmids
No data available